I recently burned the entire palm of my hand - fingers included and had blisters galore. I spread Preparation H on affected area, sat for about 1/2 hour, the pain slowly going away. I could not open my hand flat. The blisters went down, and the redness went away. I kept putting Preparation H on and by next morning there was no blisters, no pain, no redness. I did my dishes in hot water, no gloves and no pain the next morning.